Genomic Perl : from bioinformatics basics to working code / Rex A. Dwyer.
2003
QA76.73.P22 D88 2003eb
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Details
Title
Genomic Perl : from bioinformatics basics to working code / Rex A. Dwyer.
Author
ISBN
0511063393 (electronic bk.)
9780511063398 (electronic bk.)
0511057067 (electronic bk. ; Adobe Reader)
9780511057069 (electronic bk. ; Adobe Reader)
9780521801775
052180177X
9781139164764 (electronic bk.)
1139164767 (electronic bk.)
9780511071850 (electronic bk.)
051107185X (electronic bk.)
1280418214
9781280418211
1107130468
9781107130463
9786610418213
6610418217
1139147102
9781139147101
0511307551
9780511307553
9780511063398 (electronic bk.)
0511057067 (electronic bk. ; Adobe Reader)
9780511057069 (electronic bk. ; Adobe Reader)
9780521801775
052180177X
9781139164764 (electronic bk.)
1139164767 (electronic bk.)
9780511071850 (electronic bk.)
051107185X (electronic bk.)
1280418214
9781280418211
1107130468
9781107130463
9786610418213
6610418217
1139147102
9781139147101
0511307551
9780511307553
Imprint
Cambridge, UK ; New York : Cambridge University Press, 2003.
Language
English
Language Note
English.
Description
1 online resource (xvii, 334 pages) : illustrations
Call Number
QA76.73.P22 D88 2003eb
System Control No.
(OCoLC)57182371
Summary
There are many basic computational problems in molecular biology and this text gives concise, working programs to solve them using Perl. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. Perl code is provided on the accompanying CD.
Bibliography, etc. Note
Includes bibliographical references (pages 318-323) and index.
Formatted Contents Note
The Central Dogma
DNA and RNA
Chromosomes
Proteins
The Central Dogma
Transcription and Translation in Perl
RNA Secondary Structure
Messenger and Catalytic RNA
Levels of RNA Structure
Constraints on Secondary Structure
RNA Secondary Structures in Perl
Counting Hydrogen Bonds
Folding RNA
Comparing DNA Sequences
DNA Sequencing and Sequence Assembly
Alignments and Similarity
Alignment and Similarity in Perl
Predicting Species: Statistical Models
Perl Subroutine Libraries
Species Prediction in Perl
Substitution Matrices for Amino Acids
More on Homology
Deriving Substitution Matrices from Alignments
Substitution Matrices in Perl
The PAM Matrices
PAM Matrices in Perl
Sequence Databases
FASTA Format
GenBank Format
GenBank's Feature Locations
Reading Sequence Files in Perl
Object-Oriented Programming in Perl
The SimpleReader Class
Hiding File Formats with Method Inheritance
Local Alignment and the BLAST Heuristic
The Smith-Waterman Algorithm
The BLAST Heuristic
Preprocessing the Query String
Scanning the Target String
Implementing BLAST in Perl
Statistics of BLAST Database Searches
BLAST Scores for Random DNA
BLAST Scores for Random Residues
BLAST Statistics in Perl
Interpreting BLAST Output
Multiple Sequence Alignment I
Extending the Needleman-Wunsch Algorithm
NP-Completeness
Alignment Merging: A Building Block for Heuristics
Merging Alignments in Perl
Finding a Good Merge Order.
DNA and RNA
Chromosomes
Proteins
The Central Dogma
Transcription and Translation in Perl
RNA Secondary Structure
Messenger and Catalytic RNA
Levels of RNA Structure
Constraints on Secondary Structure
RNA Secondary Structures in Perl
Counting Hydrogen Bonds
Folding RNA
Comparing DNA Sequences
DNA Sequencing and Sequence Assembly
Alignments and Similarity
Alignment and Similarity in Perl
Predicting Species: Statistical Models
Perl Subroutine Libraries
Species Prediction in Perl
Substitution Matrices for Amino Acids
More on Homology
Deriving Substitution Matrices from Alignments
Substitution Matrices in Perl
The PAM Matrices
PAM Matrices in Perl
Sequence Databases
FASTA Format
GenBank Format
GenBank's Feature Locations
Reading Sequence Files in Perl
Object-Oriented Programming in Perl
The SimpleReader Class
Hiding File Formats with Method Inheritance
Local Alignment and the BLAST Heuristic
The Smith-Waterman Algorithm
The BLAST Heuristic
Preprocessing the Query String
Scanning the Target String
Implementing BLAST in Perl
Statistics of BLAST Database Searches
BLAST Scores for Random DNA
BLAST Scores for Random Residues
BLAST Statistics in Perl
Interpreting BLAST Output
Multiple Sequence Alignment I
Extending the Needleman-Wunsch Algorithm
NP-Completeness
Alignment Merging: A Building Block for Heuristics
Merging Alignments in Perl
Finding a Good Merge Order.
Digital File Characteristics
data file
Source of Description
Print version record.
Available in Other Form
Print version: Dwyer, Rex A. Genomic Perl. Cambridge, UK ; New York : Cambridge University Press, 2003
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