Protein condensation : kinetic pathways to crystallization and disease / J.D. Gunton, A. Shiryayev, and D.L. Pagan.
2007
QP551 .G86 2007eb
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Details
Title
Protein condensation : kinetic pathways to crystallization and disease / J.D. Gunton, A. Shiryayev, and D.L. Pagan.
ISBN
9780511342820 (electronic bk.)
0511342829 (electronic bk.)
0511341199
9780511341199
0511342292 (electronic bk.)
9780511342295 (electronic bk.)
1281085383
9781281085382
9780511535321 (ebook)
0511535325 (ebook)
9781107424272 (paperback)
1107424275
1107176093
9781107176096
9786611085384
6611085386
0511341776
9780511341779
0521851211 (Cloth)
9780521851213
0511342829 (electronic bk.)
0511341199
9780511341199
0511342292 (electronic bk.)
9780511342295 (electronic bk.)
1281085383
9781281085382
9780511535321 (ebook)
0511535325 (ebook)
9781107424272 (paperback)
1107424275
1107176093
9781107176096
9786611085384
6611085386
0511341776
9780511341779
0521851211 (Cloth)
9780521851213
Imprint
Cambridge, UK ; New York, N.Y. : Cambridge University Press, 2007.
Language
English
Language Note
English.
Description
1 online resource (xii, 364 pages) : illustrations
Other Standard Identifiers
9786611085384
Call Number
QP551 .G86 2007eb
System Control No.
(OCoLC)182480002
Summary
The quest to understand the condensation of proteins from solutions is a rapidly evolving field. The purpose of this book is to bring to an interdisciplinary audience the state-of-the-art in current research. The first part of the book deals with issues related to the production of high quality protein crystals from solution. Since protein function is determined by structure, high quality protein crystals must be grown in order to determine their structure by X-ray crystallography. The book also discusses diseases that occur due to undesired protein condensation, an increasingly important subject. Examples include sickle cell anemia, cataracts and Alzheimer's disease. Current experimental and theoretical work on these diseases is discussed, which seeks understanding at a fundamental, molecular level, to prevent the undesired condensation from occurring. The book, containing color plate sections, is suitable for graduate students and academic researchers in physics, chemistry, structural biology, protein crystallography and medicine.
Bibliography, etc. Note
Includes bibliographical references and index.
Formatted Contents Note
Globular protein structure
Experimental methods
Thermodynamics and statistical mechanics
Protein-protein interactions
Theoretical studies of equilibrium
Nucleation theory
Experimental studies of nucleation
Lysozyme
Some other globular proteins
Membrane proteins
Crystallins and cataracts
Sickle hemoglobin and sickle cell anemia
Alzheimer's disease.
Experimental methods
Thermodynamics and statistical mechanics
Protein-protein interactions
Theoretical studies of equilibrium
Nucleation theory
Experimental studies of nucleation
Lysozyme
Some other globular proteins
Membrane proteins
Crystallins and cataracts
Sickle hemoglobin and sickle cell anemia
Alzheimer's disease.
Digital File Characteristics
data file
Source of Description
Print version record.
Added Author
Available in Other Form
Print version: Gunton, J.D. (James D.), 1937- Protein condensation. Cambridge, UK ; New York, N.Y. : Cambridge University Press, 2007
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