880-01 Contents
Contributors
Foreword
Preface
I General Principles
Chapter 1 : Systematics of the Genus Cryptococcus and Its Type Species C. neoformans / Kyung J. Kwon-Chung, Teun Boekhout, Brian L. Wickes, Jack W. Fell
Chapter 2 : The History of Cryptococcus and Cryptococcosis / John R. Perfect, Arturo Casadevall
Chapter 3 : Biosynthesis and Genetics of the Cryptococcus Capsule / Guilhem Janbon, Tamara L. Doering
Chapter 4 : The Architecture and Antigenic Composition of the Polysaccharide Capsule / Marcio L. Rodrigues, Arturo Casadevall, Oscar Zaragoza
Chapter 5 : Melanin: Structure, Function, and Biosynthesis in Cryptococcus / David Trofa, Arturo Casadevall, Joshua D. Nosanchuk
Chapter 6 : The Cell Wall of Cryptococcus / Nicole M. Gilbert, Jennifer K. Lodge, Charles A. Specht
Chapter 7 : Sexual Reproduction of Cryptococcus / Yen-Ping Hsueh, Xiaorong Lin, Kyung J. Kwon-Chung, Joseph Heitman
Chapter 8 : Population Structure and Ecology of Cryptococcus neoformans and Cryptococcus gattii / Anastasia P. Litvintseva, Jianping Xu, Thomas G. Mitchell
II Genetics And Genomics
Chapter 9 : The Cryptococcus Genomes: Tools for Comparative Genomics and Expression Analysis / James W. Kronstad, Brendan J. Loftus, Jennifer K. Lodge
Chapter 10 : Genetic and Genomic Approaches to Cryptococcus Environmental and Host Responses / Alexander Idnurm, Peter R. Williamson
Chapter 11 : The Mating-Type Locus of Cryptococcus: Evolution of Gene Clusters Governing Sex Determination and Sexual Reproduction from the Phylogenomic Perspective / Yen-Ping Hsueh, Banu Metin, Keisha Findley, Marianela Rodriguez-Carres, Joseph Heitman
III Signaling And Virulence
Chapter 12 : G-Protein Signaling Pathways: Regulating Morphogenesis and Virulence of Cryptococcus / J. Andrew Alspaugh, Connie B. Nichols, Chaoyang Xue, Wei-Chiang Shen, Ping Wang
Chapter 13 : A Role for Mating in Cryptococcal Virulence / Kirsten Nielsen, Kyung J. Kwon-Chung
Chapter 14 : Sensing Extracellular Signals in Cryptococcus neoformans / Alexander Idnurm, Yong-Sun Bahn, Wei-Chiang Shen, Julian C. Rutherford, Fritz A. Mühlschlegel
Chapter 15 : Virulence Mechanisms of Cryptococcus gattii: Convergence and Divergence / Sudha Chaturvedi, Vishnu Chaturvedi
Chapter 16 : Drug Resistance in Cryptococcus: Epidemiology and Molecular Mechanisms / M.A. Pfaller, J.K. Lodge, M.A. Ghannoum
Chapter 17 : Signaling Cascades and Enzymes as Cryptococcus Virulence Factors / Deborah S. Fox, Julianne T. Djordjevic, Tania C. Sorrell
IV Environmental Interactions and Population Genetics
Chapter 18 : Environmental Niches for Cryptococcus neoformans and Cryptococcus gattii / Thomas G. Mitchell, Elizabeth Castañeda, Kirsten Nielsen, Bodo Wanke, Marcia S. Lazéra
Chapter 19 : Cryptococcus neoformans: Nonvertebrate Hosts and the Emergence of Virulence / Jeffrey J. Coleman, Cara J. Chrisman, Arturo Casadevall, Eleftherios Mylonakis
Chapter 20 : Cryptococcosis in Africa / Nelesh P. Govender, Thomas G. Mitchell, Anastasia P. Litvintseva, Kathleen J. Miglia
Chapter 21 : Cryptococcosis in Asia / Jiangping Xu, Weerawat Manosuthi, Uma Banerjee, Li-Ping Zhu, Janghan Chen, Shigeru Kohno, Koichi Izumikawa, Yuchong Chen, Somnuek Sungkanuparph, Thomas S. Harrison, Matthew Fisher
Chapter 22 : Sexual Reproduction of Cryptococcus gattii: a Population Genetics Perspective / Dee Carter, Leona Campbell, Nathan Saul, Mark Krockenberger
Chapter 23 : The Emergence of Cryptococcus gattii Infections on Vancouver Island and Expansion in the Pacific Northwest / Karen Bartlett, Edmond Byrnes, Colleen Duncan, Murray Fyfe, Eleni Galanis, Joseph Heitman, Linda Hoang, Sarah Kidd, Laura MacDougall, Sunny Mak, Kieren Marr, Muhammad Morshed, Sarah West, James Kronstad
Chapter 24 : Molecular Typing of the Cryptococcus neoformans/Cryptococcus gattii Species Complex / Wieland Meyer, Felix Gilgado, Popchai Ngamskulrungroj, Luciana Trilles, Ferry Hagen, Elizabeth Castañeda, Teun Boekhout
Chapter 25 : Hybridization and Its Importance in the Cryptococcus Species Complex / Massimo Cogliati, Xiaorong Lin, Maria Anna Viviani
V Interactions with the Immune System
Chapter 26 : The Interaction of Cryptococcus neoformans with Host MacroPhages and Neutrophils / Travis McQuiston, Maurizio Del Poeta
Chapter 27 : T Cell and Dendritic Cell Immune Responses to Cryptococcus / Karen L. Wozniak, Stuart M. Levitz
Chapter 28 : Acquired Humoral Immunity to Cryptococcus neoformans / Liise-Anne Pirofski, Arturo Casadevall
Chapter 29 : Interactions of Capsule with Antibody and Complement / Thomas R. Kozel
Chapter 30 : Cryptococcus Interactions with Innate Cytotoxic Lymphocytes / Shaunna M. Huston, Christopher H. Mody
VI Pathogenesis of Cryptococcosis
Chapter 31 : Cryptococcus neoformans: Latency and Disease / Françoise Dromer, Arturo Casadevall, John Perfect, Tania Sorrell
Chapter 32 : Intracellular Replication and Exit Strategies / Kerstin Voelz, Simon A. Johnston, Robin C. May
Chapter 33 : Pulmonary Innate and Adaptive Defenses against Cryptococcus / Kristi L. Williams, Floyd L. Wormley, Jr., Scarlett Geunes-Boyer, Jo Rae Wright, Gary B. Huffnagle
Chapter 34 : Invasion of Cryptococcus into the Central Nervous System / Françoise Dromer, Stuart M. Levitz
Chapter 35 : Cryptococcosis in Experimental Animals: Lessons Learned / Karl V. Clemons, David A. Stevens
Chapter 36 : Veterinary Insights into Cryptococcosis Caused by Cryptococcus neoformans and Cryptococcus gattii / Richard Malik, Mark B. Krockenberger, Carolyn R. O'Brien, Dee A. Carter, Wieland Meyer, Paul J. Canfield
VII Diagnosis, Treatment, Prevention, and Clinical Perspectives
Chapter 37 : Cryptococcosis in Transplant Recipients / Nina Singh, Barbara D. Alexander
Chapter 38 : Cryptococcosis in AIDS / Bettina C. Fries, Gary M. Cox
Chapter 39 : Antifungal Trials: Progress, Approaches, New Targets, and Perspectives in Cryptococcosis / Peter G. Pappas
Chapter 40 : Vaccines and Antibody Therapies from Cryptococcus neoformans to Melanoma / Arturo Casadevall, Ekaterina Dadachova, Liise-anne Pirofski
Chapter 41 : Diagnostic Approach Based on Capsular Antigen, Capsule Detection, [Beta]-Glucan, and DNA Analysis / Mara R. Diaz, M. Hong Nguyen
Chapter 42 : Management of Cryptococcal Meningoencephalitis in Both Developed and Developing Countries / Joseph N. Jarvis, Tihana Bicanic, Thomas S. Harrison
Chapter 43 : Public Health Importance of Cryptococcal Disease: Epidemiology, Burden, and Control / Benjamin J. Park, Shawn R. Lockhart, Mary E. Brandt, Tom M. Chiller
Chapter 44 : Clinical Perspectives on Cryptococcus neoformans and Cryptococcus gattii: Implications for Diagnosis and Management / Tania C. Sorrell, Sharon C.-A. Chen, Peter Phillips, Kieren A. Marr
Index
Color Plates.

Contributors; Foreword; Preface; SECTION I. GENERAL PRINCIPLES; SECTION II. GENETICS AND GENOMICS; SECTION III. SIGNALING AND VIRULENCE; SECTION IV. ENVIRONMENTAL INTERACTIONS AND POPULATION GENETICS; SECTION V. INTERACTIONS WITH THE IMMUNE SYSTEM; SECTION VI. PATHOGENESIS OF CRYPTOCOCCOSIS; SECTION VII. DIAGNOSIS, TREATMENT, PREVENTION, AND CLINICAL PERSPECTIVES; Index.